Abstract :
This study aimed to explore the application of different prenatal corticosteroids in the assessment of neurological
deficits and prognosis in premature infants through Magnetic Reasoning Imaging (MRI) under optimized cluster algorithm.
Methods. 100 pregnant women with threatened preterm labor were retrospectively analyzed, in which 38 pregnant women with
lasting threatened preterm labor (group A) were treated with multiple courses of antenatal corticosteroids (dexamethasone
treatment) and 62 cases of pregnant women with threatened preterm labor (group B) were treated with single course of
dexamethasone treatment. Craniocerebral MRI images based on optimal clustering algorithm were used to examine neonates.
Neonatal hypoxic-ischemic encephalopathy (HIE) rate, serum neuron-specific enolase (NSE) concentration, neonatal behavioral
neurological score (NBNA), respiratory distress syndrome (RDS) rate, perinatal mortality, neonatal birth weight, and maternal
complications rate of two groups were compared. Results. Compared with other traditional image segmentation algorithms, this
algorithm had the best segmentation effect, the shortest running time (1.43 s), the least number of iterations (5 times), and the
highest segmentation accuracy (97.98%). There was no significant difference in the HIE rate, serum NSE concentration, NBNA
score, RDS score, and perinatal mortality in group A and group B (P > 0.05). Compared with group B, neonates’ body weight in
group A was decreased, while the maternal complication rate in group A was increased (P < 0.05). Conclusion. MRI images based
on optimized clustering algorithm can be used in the diagnosis of neonatal hypoxic-ischemic encephalopathy. There is no
significant difference in the application of different antenatal corticosteroids affecting premature nerve function defect and
prognosis, but multiple courses of antenatal corticosteroids can affect neonatal body mass and increased maternal complications
to a certain extent; therefore, before threatened premature delivery treatment, the pros and cons of multiple courses of antenatal
corticosteroids should fully be considered and in the treatment, measures should be actively taken to alleviate the side effect.
