Author/Authors :
Alçelik, Aytekin Abant Izzet Baysal Üniversitesi - Arastirma ve Uygulama Hastanesi - Iç Hastaliklari Anabilim Dali, Turkey , Bicik, Zerrin SB Kartal Dr. Lütfi Kirdar Egitim ve Arastirma Hastanesi - Nefroloji Klinigi, Turkey , Belenli, Olcay SB Diskapi Yildirim Beyazit Egitim ve Arastirma Hastanesi - Patoloji Klinigi, Turkey , Gergin, Rezan Abant Izzet Baysal Üniversitesi - Tip Fakültesi Düzce Hastanesi - Iç Hastaliklari Anabilim Dali, Turkey , Korkmaz, Ugur Kocaeli Üniversitesi - Tip Fakültesi - Gastroenteroloji Bilim Dali, Turkey
Abstract :
The diagnosis of Anderson-Fabry disease can be made by careful history and physical examination if some of the typical clinical features are present. Renal manifestations occur in approximately 50% of affected patients particularly men, by the age of 35 years, and the incidence increases significantly with age. Early diagnosis of Fabry disease is very important. End-stage renal disease was the most common cause of death in Fabry patients before the development of dialysis and renal transplantation. Nephrotic-range proteinuria was uncommon and only a fourth of them developed nephrotic syndrome. Here, we have reported a Fabry’s patient presented with nephrotic syndrome and hepatitis B seropositivity as an unusual presentation.
Keywords :
Fabry disease , nephrotic syndrome , hepatitis B , renal biopsy
