Author/Authors :
Min, Kyoung Jeen Department of Emergency Medicine - Gachon University Gil Medical Center - Incheon, Korea , Kim, Jin Joo Department of Emergency Medicine - Gachon University Gil Medical Center - Incheon, Korea , Hwang, In Cheol Department of Emergency Medicine - Gachon University Gil Medical Center - Incheon, Korea , Woo, Jae Hyuk Department of Emergency Medicine - Gachon University Gil Medical Center - Incheon, Korea , Lim, Yong Su Department of Emergency Medicine - Gachon University Gil Medical Center - Incheon, Korea , Yang, Hyuk Jun Department of Emergency Medicine - Gachon University Gil Medical Center - Incheon, Korea , Lee, Keun Department of Emergency Medicine - Gachon University Gil Medical Center - Incheon, Korea
Abstract :
Background: The aim of this study was to investigate the relationships between left ventricular ejection fraction (LVEF) and mortality
and neurologic outcomes with post-cardiac arrest syndrome (PCAS) after out-of-hospital cardiac arrest (OHCA).
Methods: Patients with PCAS after OHCA admitted to the intensive care unit between January 2014 and December 2015 were analyzed retrospectively.
Results: A total of 104 patients were enrolled in this study. The mean age was 54.4 ± 15.3 years, and 75 of the patients were male
(72.1%). Arrest with a cardiac origin was found in 55 (52.9%). LVEF < 45%, 45-55%, and > 55% was measured in 39 (37.5%), 18 (17.3%),
and 47 (45.2%) of patients, respectively. In multivariate analysis, severe LV dysfunction (LVEF < 45%) was significantly related to 7-day
mortality (odds ratio 3.02, 95% Confidence Interval 1.01-9.0, p-value 0.047).
Conclusions: In this study, moderate to severe LVEF within 48 hours after return of spontaneous circulation was significantly related
to 7-day short-term mortality in patients with PCAS after OHCA. Clinicians should actively treat myocardial dysfunction, and further
studies are needed.
