Author/Authors :
Oguntibeju, Oluwafemi O. Department of Biomedical Sciences - Faculty of Health and Wellness Sciences - Cape Peninsula University of Technology - Cape Town, South Africa , Motswaledi, Modisa S. Department of Biomedical Sciences - Faculty of Health and Wellness Sciences - Cape Peninsula University of Technology - Cape Town, South Africa , Kasvosve, Ishmael Department of Medical Laboratory Sciences - Faculty of Health Sciences - University of Botswana - Gaborone, Botswana
Abstract :
Atheromatous lesions are formed by macrophages and low-density lipoprotein cholesterol invading the vascular intima. Here we show that increasing cholesterol levels are associated with peripheral monocyte depletion and this imbalance is aggravated by carriage of Lu/BCAM leukocyte adhesion molecules. This is true only in HIV infection and probably explains the risk of atherosclerosis observed in HIV-positive patients.
Keywords :
Atherosclerosis , Lu/BCAM , Non-high-density lipoprotein cholesterol , cholesterol
