Title of article
Potential role of Lu/BCAM in HIV-related atherosclerosis
Author/Authors
Oguntibeju, Oluwafemi O. Department of Biomedical Sciences - Faculty of Health and Wellness Sciences - Cape Peninsula University of Technology - Cape Town, South Africa , Motswaledi, Modisa S. Department of Biomedical Sciences - Faculty of Health and Wellness Sciences - Cape Peninsula University of Technology - Cape Town, South Africa , Kasvosve, Ishmael Department of Medical Laboratory Sciences - Faculty of Health Sciences - University of Botswana - Gaborone, Botswana
Pages
4
From page
1
To page
4
Abstract
Atheromatous lesions are formed by macrophages and low-density lipoprotein cholesterol invading the vascular intima. Here we show that increasing cholesterol levels are associated with peripheral monocyte depletion and this imbalance is aggravated by carriage of Lu/BCAM leukocyte adhesion molecules. This is true only in HIV infection and probably explains the risk of atherosclerosis observed in HIV-positive patients.
Keywords
Atherosclerosis , Lu/BCAM , Non-high-density lipoprotein cholesterol , cholesterol
Journal title
African Journal of Laboratory Medicine
Serial Year
2019
Record number
2622426
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