Author/Authors :
Torabi, Sara Faculty of Medicine - Tehran University of Medical Sciences, Tehran, Iran , Bahreini, Farbod Department of Biochemistry - Faculty of Biological Sciences - Tarbiat Modares University, Tehran, Iran , Rezaei, Nima Department of Immunology - School of Medicine - Tehran University of Medical Sciences, Tehran, Iran
Abstract :
The novel coronavirus disease (COVID-19) has affected people around the world both physi-cally and psychologically. As result, developing a coronavirus-specific vaccine and/or therapeutics is now a top priority for public health agencies. Since our findings of COVID-19 are relatively new, the current knowledge about the molecular mechanism involved in pathogenicity and virulence of the novel coro-navirus is not advanced. Understanding angiotensin-converting enzyme 2 (ACE2), the receptor for the coronavirus, is significantly important. To better illustrate the role of ACE2 in the severity of COVID-19 and the impact of currently used drugs on this receptor, this paper briefly reviews newly published articles in this regard. (www.actabiomedica.it)