Author/Authors :
Zegarska, Barbara Chair of Cosmetology and Aesthetic Dermatology - Ludwik Rydygier’s Collegium Medicum in Bydgoszcz - Nicolaus Copernicus University in Torun, Poland , Pietkun, Katarzyna Chair of Cosmetology and Aesthetic Dermatology - Ludwik Rydygier’s Collegium Medicum in Bydgoszcz - Nicolaus Copernicus University in Torun, Poland , Giemza-Kucharska, Paulina Clinica Dermatoestetica, Bydgoszcz, Poland , Zegarski, Tomasz Centre for Physical Education and Sport - Ludwik Rydygier’s Collegium Medicum in Bydgoszcz - Nicolaus Copernicus University in Torun, Poland , Nowacki, Maciej S. Chair and Department of Surgical Oncology - Ludwik Rydygier’s Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun - Oncology Centre-Professor Franciszek Łukaszczyk Memorial Hospital in Bydgoszcz, Poland , Romańska-Gocka, Krystyna Chair of Cosmetology and Aesthetic Dermatology - Ludwik Rydygier’s Collegium Medicum in Bydgoszcz - Nicolaus Copernicus University in Torun, Poland
Abstract :
Introduction
During the process of skin ageing, changes occur in all skin layers and all cells, including the Langerhans cells.
Aim
To assess whether any quantitative difference in the number of CD1a+ LC cells/mm2 and HLA-DR+ LC cells/mm2 as well as in their morphological features can be observed during the course of different types of skin ageing.
Material and methods
The study was conducted in a group of 60 women, which was divided into three independent groups: group I with symptoms of menopausal skin ageing, group II with symptoms of photoageing, group III with symptoms of chronological ageing. Skin biopsy samples were taken from the pre-auricular region from all of the participants. The number of CD1a+ LC cells/mm2 and HLA-DR+ LC cells/mm2 as well as their morphological features were evaluated.
Results
The frequency of CD1a+ LC and HLA-DR+ LC in all the studied groups was diverse. In groups I and III, the LC with large cell bodies and long, multi-branched processes were the majority. In group II, the LC had small cell bodies and their processes were mainly short and unbranched.
Conclusions
The obtained results indicate the presence of quantitative and morphological changes of the CD1a+ LC and HLA-DR+ LC during the course of different types of skin ageing.
