Title of article :
Crystallographic and spectroscopic characterization of 2-[(7-acetyl-4-cyano-6-hydroxy-1,6-dimethyl-8-phenyl-5,6,7,8-tetrahydroisoquinolin-3-yl)sulfanyl]-N-phenylacetamide
Author/Authors :
Al-Taifi, Elham A. Department of Chemistry - Faculty of Science - Sana'a University, Sana'a, Yemen , Maraei, Islam S. Department of Chemistry - Faculty of Science - Assiut University, Assiut, Egypt , Bakhite, Etify A. Department of Chemistry - Faculty of Science - Assiut University, Assiut, Egypt , Demirtas, Güneş Ondokuz Mayıs University - Faculty of Arts and Sciences - Department of Physics, Turkey , Mague, Joel. T. Department of Chemistry - Tulane University,USA , Mohamed, Shaaban K. Chemistry and Environmental Division - Manchester Metropolitan University, England , Ramli, Youssef Laboratory of Medicinal Chemistry, Drug Sciences Research Center - Faculty of Medicine and Pharmacy - Mohammed V University in Rabat, Morocco
Abstract :
In the title molecule, C28H27N3O3S, the heterocyclic portion of the tetrahydroisoquinoline unit is planar and an intramolecular N—HN hydrogen bond and a C—H(ring) interaction help to determine the overall conformation. In the crystal, a layer structure with the layers parallel to (101) is generated by O—
HO and C—HO hydrogen bonds.
Keywords :
crystal structure , tetrahydroisoquinoline , phenylacetamide , hydrogen bond , C—H⋯π(ring) interaction
