Author/Authors :
Anstey, Matthew Harry Department of Intensive Care - Sir Charles Gairdner Hospital - Perth, Australia , Luu, Jacky Department of Intensive Care - Sir Charles Gairdner Hospital - Perth, Australia , Myers, Erina Department of Intensive Care - Sir Charles Gairdner Hospital - Perth, Australia , Palmer, Robert N Department of Intensive Care - Sir Charles Gairdner Hospital - Perth, Australia , Wibrow, Bradley Department of Intensive Care - Sir Charles Gairdner Hospital - Perth, Australia , Ho, Kwok M Department of Intensive Care - Royal Perth Hospital - Perth, Australia
Abstract :
The current coronavirus disease 2019 (COVID-19) pandemic has re-ignited interest in using
adjunctive agents—including corticosteroids and vitamin C—to attenuate the severity of viral
pneumonia and acute lung injury [1,2]. Although the efficacy of dexamethasone on COVID-19 seems convincing, the role of corticosteroids with and without vitamin C in other viral
pneumonia remains contentious and unclear. We hypothesised that high dose intravenous
vitamin C (6 g/day) used in conjunction with corticosteroids could improve oxygenation in
non–COVID-19 viral pneumonia.
