Author/Authors :
Évora, Paulo Roberto Barbosa Department of Surgery and Anatomy - Faculdade de Medicina de Ribeirão Preto - Universidade de São Paulo (FMRP-USP), Ribeirao Preto-SP, Brazil , Albuquerque, Agnes Afrodite Sumarelli Department of Surgery and Anatomy - FMRP–USP, Ribeirao Preto-SP, Brazil. , Nadai, Tales Rubens de Department of Surgery and Anatomy - FMRP-USP, Ribeirao Preto-SP, Brazil , Mente, Enio David Department of Surgery and Anatomy - FMRP-USP, Ribeirao PretoSP, Brazil , Sankarankuty, Ajith Kumar Department of Surgery and Anatomy - FMRP-USP, Ribeirao PretoSP, Brazil , Castro-e-Silva, Orlando Surgery and Anatomy Department - FMRP-USP, Ribeirao Preto-SP, Brazil
Abstract :
Early cancer diagnosis, new therapies that increased survival of patients, besides the increasingly elderly population are some factors would be associated with possible cancer dissemination in patients under cardiopulmonary bypass (CPB) cardiac surgery. Also, the benefits, and risks, regarding long-term survival, have not yet been established. Therefore, cardiac surgery morbimortality may be superior in patients with cancer disease. Also, immunologic and inflammatory changes secondary to CPB can also increase tumor recurrence. After a brief introduction and CPB immunologic the two main topic subjects included: 1) Combined heart surgery and lung resection and; 2) Possible influence of neoplasia type. After observing the relative literature scarcity, we keep the opinion that “CPB has a modest association with cancer progression” and that “CPB and cancer dissemination should be a logical but unlikely association.”