Title of article :
Antibiotic resistance and NG-MAST sequence types of Neisseria gonorrhoeae isolates in Poland compared to the world
Author/Authors :
Mlynarczyk-Bonikowska, Beata Department of Diagnostics of Sexually Transmitted Diseases - Medical University of Warsaw, Poland , Malejczyk, Magdalena Department of Diagnostics of Sexually Transmitted Diseases - Medical University of Warsaw, Poland , Majewski, Sławomir Department of Dermatology and Venereology - Medical University of Warsaw, Poland , Unemo, Magnus World Health Organization (WHO) Collaborating Centre for Gonorrhoea and other STIs - Faculty of Medicine and Health - Örebro University, Sweden
Abstract :
Gonorrhoea is one of the most common sexually transmitted infections and in 2012, the World Health Organization estimated about 78 million of new global urogenital cases among adults per year. The main concern during the latest decade has been the emergence and spread of multidrug-resistant strains of Neisseria gonorrhoeae. Resistance has emerged internationally to the extended-spectrum cephalosporins, ceftriaxone and cefixime, which are the last remaining options for empiric first-line monotherapy of gonorrhoea. In Poland, the levels of resistance to ciprofloxacin, benzylpenicillin and tetracycline are high, and the prevalence of azithromycin resistance has increased. However, no resistance to ceftriaxone has been identified. The currently spread multidrug-resistant strains frequently represent epidemic clones. The present paper reviews and describes the antimicrobial resistance and N. gonorrhoeae multiantigen sequence typing (NG-MAST) sequence types of N. gonorrhoeae strains spreading in Poland compared to the world.
Keywords :
Neisseria gonorrhoeae , gonorrhoea , antimicrobial resistance , ceftriaxone , azithromycin , NG-MAST , sequence type , genogroup
Journal title :
Advances in Dermatology and Allergology/Postȩpy Dermatologii i Alergologii
