Author/Authors :
Ezawa, Toshinari Faculty of Pharmacy and Pharmaceutical Science - Josai University, Japan , Inoue, Yutaka Faculty of Pharmacy and Pharmaceutical Science - Josai University, Japan , Murata, Isamu Faculty of Pharmacy and Pharmaceutical Science - Josai University, Japan , Suzuki, Mitsuaki Faculty of Science - Josai University, Japan , Takao, Koichi Faculty of Pharmacy and Pharmaceutical Science - Josai University, Japan , Sugita, Yoshiaki Faculty of Pharmacy and Pharmaceutical Science - Josai University, Japan , Kanamoto, Ikuo Faculty of Pharmacy and Pharmaceutical Science - Josai University, Japan
Abstract :
The title compounds, 5-(2H-1,3-benzodioxol-5-yl)-N-cyclohexylpenta-2,4-dienamide, C18H21NO3 (I), and 5-(2H-1,3-benzodioxol-5-yl)-1-(pyrrolidin-1-yl)penta-2,4-dien-1-one C16H17NO3 (II), are derivatives of piperine, which is known as a pungent component of pepper. Their geometrical parameters are similar to those of the three polymorphs of piperine, which indicate conjugation of electrons over the length of the molecules. The extended structure of (I) features N—H⋯O amide hydrogen bonds, which generate C(4) [010] chains. The crystal of (II) features aromatic π–π stacking, as for two of three known piperine polymorphs.
Keywords :
crystal structure , ; organic crystal , piperine , hydrogen bond
