Author/Authors :
Mahjoob, Mohammad Parsa Cardiovascular Research Center - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Alipour Parsa, Saeed Cardiovascular Research Center - Modarres hospital - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Mazarei, Asghar Cardiovascular Research Center - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Safi, Morteza Cardiovascular Research Center - Modarres hospital - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Khaheshi, Isa Cardiovascular Research Center - Modarres hospital - Shahid Beheshti University of Medical Sciences, Tehran, Iran , Esmaeeli, Shooka Student’s Scientific Research Center (SSRC) - Tehran University of Medical Sciences (TUMS
Abstract :
Aims:To detect the significance of coronary artery disease in the patients, who are suspected, was assumed to be one of the advantages of 2D STE, as a novel non-invasive imaging modality with acceptable accuracy. Methods: In this study, 216 patients who were suspected to have coronary artery disease and can-didate for coronary angiography, underwent rest two-dimensional speckle tracking echocardiography (2D STE) and negative global systolic longitudinal strain was evaluated. Results: Negative global systolic left ventricular longitudinal strain under 18% in rest 2D-STE was significantly prevalent in patients with signifi-cant CAD in coronary angiography (P value<0.0001).Our results revealed sensitivity of 91.1%, specificity of 63.0%, positive predictive value of 80.4%, negative predictive value of 81.0% and accuracy of 80.5% for rest 2D-STE in detection of significant CAD. Conclusion: Here in we showed that rest Two-dimensional speckle tracking echocardiography could be a sensitive but nonspecific imaging modality to determine significant cor-onary artery disease. Future studies with large size will reveal more detailed findings. (www.actabiomedica.it)
