Title of article :
Guillain-Barre Syndrome Due to Tramadol
Author/Authors :
Banagozar Mohammadi ، Ali Department of Internal Medicine - School of Medicine - Tabriz University of Medical Sciences , Ostadi ، Ali Department of Internal Medicine - School of Medicine - Tabriz University of Medical Sciences , Paeezi ، Maryam Department of Forensic Medicine and Toxicology - Loghman Hakim Hospital, School of Medicine - Shahid Beheshti University of Medical Sciences , Mostafazadeh ، Babak Toxicological Research Center - Shahid Beheshti University of Medical Sciences
Abstract :
Tramadol is a powerful prescription medication used for pain relief of varying intensities. Tramadol was initially produced in Germany to alleviate postsurgical and chronic pains. We describe a case of a 22-year-old male with no past medical history who took tramadol for the second time and then had a tonic-clonic seizure episode that worsened the weakness of his inferior limbs and followed by loss of consciousness. According to physical examination, clinical and paraclinical tests, he was diagnosed with Guillain-Barre syndrome. After treatment with intravenous immunoglobulin, he was improved and discharged 9 days after treatment. He was recommended to continue physiotherapy. The relation between tramadol using and Guillain- Barre syndrome development is unknown but it can be due to reactive oxygen species generation.
Keywords :
Tramadol , Gillian , Barre syndrome , Reactive oxygen species , Seizure
Journal title :
International Journal of Medical Toxicology and Forensic Medicine
Journal title :
International Journal of Medical Toxicology and Forensic Medicine
