Author/Authors :
Gök ، Gulay Department of Cardiology - Faculty of Medicine - Medipol University , Karadağ ، Mehmet Department of Biostatistics - Faculty of Medicine - Hatay Mustafa Kemal University , Çinar ، Tufan Department of Cardiology - Abdülhamid Han Training and Research Hospital - Health Sciences University , Nurkalem ، Zekeriya Department of Cardiology - Faculty of Medicine - Medipol University , Duman ، Dursun Department of Cardiology - Faculty of Medicine - Medipol University
Abstract :
Introduction: The aim of this study was to evaluate the inhospital and shortterm predictive factors of mortality in intermediatehigh risk acute pulmonary embolism (PE) patients with right ventricle (RV)dysfunction and myocardial injury. Methods: In this retrospective study, the medical records of 187 patients with a diagnosis of intermediate high risk acute PE were evaluated. A contrastenhanced multidetector pulmonary angiography was used to confirm diagnosis in all cases. Allcause mortality was determined by obtaining both in hospital and 30 days followup data of patients from medical records. Results: During the inhospital stay (9.5±4.72 days), 7 patients died, resulting in an acute PE related inhospital mortality of 3.2%. Admission heart rate (HR), (Odds ratio (OR), 1.028 95% Confidence interval (CI), 0.0021.121; P = 0.048) and blood urea nitrogen (BUN) (OR, 1.028 95% CI, 0.0021.016; P = 0.044) were found to be independent predictors for inhospital mortality in a multi variate logistic regression analysis. In total, 32 patients (20.9%) died during 30 days followup.The presence of congestive heart failure (OR, 0.015, 95%CI, 0.0010.211; P = 0.002) and dementia (OR, 0.029, 95%CI,0.0020.516; P = 0.016) as well as low albumin level (OR, 0.049 95%CI, 0.0060.383; P = 0.049) were associated with 30 days mortality. Conclusion: HR and BUN were independent predictors of inhospital mortality and the presence of congestive heart failure, dementia, and low albumin levels were associated with higher 30 days mortality.
