Title of article :
Resolved of Respiratory Failure Following the Use Pulse-Doses of Methylprednisolone in a Cytokine Storm Related to 2019 novel coronavirus
Author/Authors :
Khederlou, Hamid Tehran Heart Center - Tehran University of Medical Sciences, Tehran, Iran , Rostamian, Abdolrahman Rheumatology Department - Imam Khomeini Hospital - Tehran University of Medical Sciences, Tehran, Iran , Nezhadseifi, Elham Rheumatology Department - Imam Khomeini Hospital - Tehran University of Medical Sciences, Tehran, Iran , Ebrahimi-louyeh, Hourvash Rheumatology Department - Imam Khomeini Hospital - Tehran University of Medical Sciences, Tehran, Iran
Pages :
5
From page :
129
To page :
133
Abstract :
Since mid-December of 2019, an outbreak of pneumonia has been spread from Wuhan City, Hubei province, China, as a viral pneumonia. After virus identification and isolation, the pathogen for this pneumonia was originally called 2019 novel coronavirus (2019-nCoV). 2019-nCoV has been associated with progressive cytokine storm leading to a hyper-inflammatory state that this state associated with respiratory failure. We hereby reported a known case of Rheumatoid arthritis, Hypertension and Coronary artery bypass graft that confirmed 2019-nCoV and he was associated with progressive cytokine storm leading to respiratory failure. After corticosteroid administration, respiratory failure and extremely high levels of IL6 responded dramatically to pulse-doses of Methylprednisolone. We concluded that pulse-doses of Corticosteroids can be effective in controlling and relieving cytokine storms and related respiratory failure.
Farsi abstract :
فاقد چكيده فارسي
Keywords :
Cytokine storm , Interleukin-6 , 2019 Novel coronavirus , Respiratory failure , Systemic corticosteroid
Journal title :
Rheumatology Research
Serial Year :
2020
Record number :
2630158
Link To Document :
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