Title of article :
A multi-component reaction for the direct access to 4,4’-(phenylmethylene)bis(1H-pyrazol-5-ol)-3-carboxylates using nano-NiZr4(PO4)6 in water
Author/Authors :
Safaei-Ghomi ، Javad Department of Organic Chemistry - Faculty of Chemistry - University of Kashan , Shahbazi-Alavi ، Hossein Department of Organic Chemistry - Faculty of Chemistry - University of Kashan , Ziarati ، Abolfazl School of Chemistry, College of Science - University of Tehran
Abstract :
An efficient synthesis of 4,4’(phenylmethylene)bis(1Hpyrazol5ol)3carboxylates is achieved by one pot pseudo fivecomponent reaction of phenylhydrazine, acetylenedicarboxylates and aromatic aldehydes in the presence ofnanoNiZr4(PO4)6 at 60°C in water. NanoNiZr4(PO4)6 has been characterized by powder Xray diffraction (XRD) and scanning electronic microscopy (SEM). Use of simple and readily available starting materials, excellent yields in short times, reusability of the catalyst, little catalyst loading and simple operational procedures are some of the important features of this protocol.
Keywords :
Multi , component , Water , Pyrazole , Catalyst , One , pot , Nano , NiZr4(PO4)6
Journal title :
Scientia Iranica(Transactions C: Chemistry, Chemical Engineering)
Journal title :
Scientia Iranica(Transactions C: Chemistry, Chemical Engineering)
