Author/Authors :
Ollé-Goig, JE Catalan Association for the Control of Tuberculosis in the Third World (ACTMON), Spain , Ramírez, J University of Barcelona - Institut d Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) - Pathology Department, Hospital Clinic, Spain , Cervera, C University of Barcelona - Institut d Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) - Infectious Diseases Service, Hospital Clinic, Spain , Miró, JM University of Barcelona - Institut d Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) - Infectious Diseases Service, Hospital Clinic, Spain
Abstract :
Idiopathic CD4+ lymphocytopenia is a disorder associated with low CD4+ T cell count and opportunistic infections resembling AIDS. Most cases are described in developed countries. We report two HIV-negative patients with idiopathic CD4+ lymphocytopenia and AIDS-defining events diagnosed in Djibouti. The first patient developed lesions of Kaposi’s sarcoma and the second one presented with pulmonary tuberculosis. Both patients died with severe immunodepression. In poor resource-areas where HIV testing may not be available it is important to bear in mind that severe immunodepression and a clinical presentation compatible with AIDS do not necessary carry the diagnosis of AIDS.
Keywords :
Human immunodeficiency virus , Acquired immunodeficiency syndrome , Lymphopenia , Kaposi’s sarcoma , tuberculosis , Djibouti.