The Effectiveness of Aerobic Training With Supplementation With Vitamins C and E on Some Inflammatory and Cardiovascular Risk Factors in Overweight Men

Background: The purpose of this study was to investigate the effectiveness of aerobic training with supplementation of vitamins C and E on some inflammatory markers and cardiovascular risk factors in overweight men. Methods: In this semiexperimental study, 30 overweight men were randomly assigned into three groups (n=10, AT+Sup, AT+Placebo, and control). The exercise program consisted of three sessions per week at the intensity of 60-75% of maximal heart rate for six weeks. The supplement group received 300 mg of vitamin E daily and 400 mg vitamin C tablet and the placebo group received one gelatin capsule daily during this period. Before and after six weeks of intervention, were measured interleukin6 (IL-6), reactive protein (CRP), Triglyceride (TG), Low-Density Lipoprotein (LDL), High-Density Lipoprotein (HDL), and insulin resistance index. Data were analyzed by t-test, one-way ANOVA, and Tukey post hoc test at a significance level of P 0.05. Result: The results showed that aerobic training significantly reduced the body fat percentage, TG, and LDL in both supplement and placebo groups(P 0.05). However, this reduction was observed in IL-6 and CRP only in the supplement group (P 0.05). On the other hand, the results showed that exercise and supplementation did not change the insulin resistance of subjects. The results of oneway ANOVA showed that there was a significant difference between the three groups in fat percentage, IL-6, CRP, TG, and LDL (P 0.05). Conclusion: According to the results of this research, probably six weeks of aerobic training plus supplementation with vitamin E and C may help to reduce inflammatory symptoms, body fat percentage, and some cardiovascular risk factors.