مرکز منطقه ای اطلاع رساني علوم و فناوري - Stroke prevalence amongst sickle cell disease patients in Nigeria: a multi-centre study

Author/Authors :

Jude, Madu Anazoeze University of Nigeria, Enugu Campus (UNEC) - Department of Haematology and Immunology, Nigeria , Aliyu, Galadanci Najiba Aminu Kano Teaching Hospital - Department of Haematology, Nigeria , Nalado, Aisha Mohammed Aminu Kano Teaching Hospital - Department of Haematology, Nigeria , Garba, Kangiwa Umar Federal Medical center - Department of Haematology, Nigeria , Fowodu, O Florence University College Hospital - Department of Haematology, Ibadan , Hassan, Ahmed Ahmadu Bello University Teaching Hospital - Department of Haematology, Nigeria , Inyama, Marcus University of Calabar Teaching Hospital - Department of Haematology, Nigeria , Akinpelu, Oluwaseun Ladoke Akintola University of Technology - Department of Haematology, Nigeria , Theresa, Nwagha University of Nigeria, Enugu Campus (UNEC) - Department of Haematology Immunology, Nigeria , Godswill, Ibegbulam Obike University of Nigeria, Enugu Campus (UNEC) - Department of Haematology Immunology, Nigeria , Sunday, Ocheni University of Nigeria, Enugu Campus - Department of Haematology and Immunology, Nigeria , Ifeoma, Emodi University of Nigeria, Enugu Campus - Department of Paediatrics, Nigeria , Anthony, Ikefuna University of Nigeria, Enugu Campus - Department of Paediatrics, Nigeria , Batholomew, Chukwu University of Nigeria, Enugu Campus - Department of Paediatrics, Nigeria , Chide, Okocha E Nnamdi Azikiwe University - Department of Haematology, Nigeria , Joseph, Orkuma Benue state Unversity - Department of Haematology, Nigeria , Malachy, Iheanacho Federal Medical Center - Department of Haematology, Nigeria , Korubo, Kaladada University of Port Harcourt Teaching Hospital - Department of Haematology, Nigeria , Sabastine, Anike Uchenna University of Nigeria Teaching hospital - Department of Haematology Immunology, Nigeria , Kingsley, Agu University of Nigeria Teaching hospital - Department of Haematology Immunology, Nigeria , Nonyelu, Charles University of Nigeria Teaching hospital - Department of Haematology Immunology, Nigeria , Ugwu, Angela University of Nigeria Teaching hospital - Department of Haematology Immunology, Nigeria , Duru, Augustin University of Nigeria Teaching hospital - Department of Haematology Immunology, Nigeria , Anigbo, Chukwudi University of Nigeria Teaching hospital - Department of Haematology Immunology, Nigeria , Eze, Alozie University of Nigeria Teaching hospital - Department of Haematology Immunology, Nigeria , Chukwurah, Awele University of Nigeria Teaching hospital - Department of Haematology Immunology, Nigeria , Ololo, Uchenna University of Nigeria Teaching hospital - Department of Haematology Immunology, Nigeria , Omoti, Caroline University of Benin Teaching Hospital - Department of Haematology, Nigeria , Agwu, Obineche University of Nigeria Teaching hospital - Department of Haematology Immunology, Nigeria , Iheanyi, Okpala University of Nigeria Teaching hospital - Department of Haematology Immunology, Nigeria

Abstract :

Background: Stroke is a life-changing, debilitating complication of sickle cell disease (SCD). Previous studies had recorded high stroke prevalence amongst this group of patients. Nigeria has a large population of people affected by this condition and this study aims to assess the stroke prevalence in this large population. Methodology: Stroke prevalence data from 14 physicians working in 11 tertiary health centres across the country was collated by doctors using the sickle cell registers and patient case notes. This data was then collated and used to obtain the overall stroke prevalence in adult and children. Results: The stroke prevalence in sickle cell disease patients in Nigeria was observed to be 12.4 per 1000 patients. Prevalence in the adult patients was 17.7 per 1000 patients and 7.4 per 1000 patients in children. Twenty three percent of the affected patients had more than stroke episode. Conclusion: The stroke prevalence in Nigeria is lower than previously recorded rates and further studies will be required to investigate other factors which may play a role.