Title of article :
A Case of Erythema Multiforme Caused by Sildenafil Plus Tramadol
Author/Authors :
Ghanbarzamani ، Amir Hossein Department of Clinical pharmacy - Pharmaceutical Research Center - Mazandaran University of Medical Sciences , Salehifar ، Ebrahim Department of Clinical pharmacy - Pharmaceutical Research Center - Mazandaran University of Medical Sciences , Kazemian ، Kaveh Department of Clinical Pharmacy - Sina Hospital - Tehran University of Medicine
Abstract :
In this report, we present a 29-year-old man who experienced EM five days after using sildenafil and tramadol. Based on clinical examination and history, the diagnosis of EM was made confirmed via skin biopsy, which found intraepidermal bulla filled by fibrinous exudate, some mononuclear cells, and a few eosinophils. The spongiotic epidermis showed lichenoid interface dermatitis, eosinophilic spongiosis, and necrolysis, consistent with EM diagnosis. Fluocinolone, 0.025% ointment, was prescribed for the patient, and the lesions healed after two weeks of treatment.
Keywords :
Erythema multiforme , Sildenafil , Tramadol
Journal title :
Pharmaceutical and Biomedical Research
Journal title :
Pharmaceutical and Biomedical Research
