Author/Authors :
Alaghband-Rad, Javad tehran university of medical sciences tums - Roozbeh Hospital,Faculty of Medicine - Department of Psychiatry, تهران, ايران , Nikvarz, Naemeh kerman university of medical sciences - Faculty of Pharmacy - Department of Pharmacotherapy, ايران , Tehrani-Doost, Mehdi tehran university of medical sciences tums - Roozbeh Hospital,Faculty of Medicine - Department of Psychiatry, تهران, ايران , Ghaeli, Padideh tehran university of medical sciences tums - Research Center for Rational Use of Drugs , Faculty of Pharmacy - Department of Clinical Pharmacy, تهران, ايران
Abstract :
Stuttering is a complex speech disorder. There are two forms of stuttering: developmental stuttering and acquired stuttering. Developmental stuttering is a disorder of early childhood but acquired stuttering can develop at any age. Some medications can induce or deteriorate stuttering as an adverse effect. There are several reports of stuttering due to psychotropic drugs. Memantine, a glutamate antagonist used in the treatment of Alzheimer’s disease, has also been studied for the treatment of autism spectrum disorders. This report presents deterioration of stuttering and speech problemin two children with autistic disorder who were receiving memantine. Based on our knowledge, this is the first time these adverse drug reactions have been attributed to memantine. In conclusion clinicians should consider that speech problems including stuttering may be due to the consumption of memantine, especially, in children may be a side effect of memantine especially in children.
