Three dimensional endometrial volume versus endometrial thickness measurement in prediction of IVF/ICSI outcome

Objective: To investigate the role of estimating endometrial volume and it s correlation with endometrial thickness, onthe day of hCG, in prediction of IVF outcome.Design: A prospective clinical study.Materials and methods: Endometrial volume and endometrial thickness were measured in women undergoing anIVF/ICSI cycle, on the day of HCG, using the 3 D transvaginal ultrasound probe (Sonoace 9900 Medison -Kretz ,korea). Patients were divided according to endometrial volume calculated into 3 subgroups; 2ml, 2-4ml, and 4ml, as well as according to endometrial thickness into 3 groups; 8mm, 8-12mm and 12mm. Pregnancy rates were compared between all groups.Results: The study included 103 women with no significant difference in background characteristics between all subgroups. The pregnancy rates between the three groups of endometrial volume; 2ml, 2-4ml, and 4 ml was;42%, 36% and 48% respectively. Pregnancy rates between the three groups of endometrial thickness was 25%, 40%and 50 % for 8mm, 8-12and 12mm respectively. There was no significant difference in pregnancy rates between all groups in relation to both endometrial volume and endometrial thickness.Conclusion: Endometrial volume on day of hCG is not a better predictor than endometrial thickness for determining outcome of IVF/ICSI cycles.