Author/Authors :
Paraskeva, Anteia University of Athens - Medical School, Aretaieion Hospital - Department of Anesthesiology, Greece , Vassiliou, I University of Athens - Medical School, Aretaieion Hospital - Department of Anesthesiology, Greece , Vlachos, S University of Athens - Medical School, Aretaieion Hospital - Department of Anesthesiology, Greece
Abstract :
Thrombotic thrombocytopenic purpura is a rare disease with an incidence of 3-7 cases per million and consists of thrombocytopenia, microangiopathic hemolytic anemia, neurological impairment and renal failure. The recent speculation of its pathogenetic mechanism is focused on the deficiency of Von Willebrand factor-cleaving metalloprotease activity.
