Title of article :
Topical calcipotriol in dermatology
Author/Authors :
Shahzad, Atif King Edward Medical University - Mayo Hospital - Department of Dermatology, Unit II, Pakistan , Shahzad, Muhammad King Edward Medical University - Mayo Hospital - Department of Dermatology, Pakistan , Khurshid, Khawar King Edward Medical University - Mayo Hospital - Department of Dermatology, Unit II, Pakistan
Abstract :
Calcipotriol is a vitamin D analogue, which has antiproliferative and anti-inflammatory effects and stimulates terminal differentiation of keratinocytes by acting through immunologic mechanism and regulating intracellular calcium concentration. It is currently being used in many dermatoses e.g. psoriasis, vitiligo, morphoea, pityriasis rubra pilaris, ichthyoses and palmoplantar keratodermas. The present article reviews the therapeutic potential of topical calcipotriol in various dermatological disorders.
Keywords :
Calcipotriol , dermatological disorders
Journal title :
Journal of Pakistan Association of Dermatologists
Journal title :
Journal of Pakistan Association of Dermatologists