Role of correct dose of zinc sulphate in the treatment of acrodermatitis enteropathica in two siblings

Acrodermatitis enteropathica is a rare autosomal recessive disorder, caused by impaired absorption of zinc from gastrointestinal tract and results in several physical and psychological effects. It typically causes perioral and perigenital eczematous rash. The disease is treated by zinc sulphate powder but while calculating the dose of powder, due attention is not given to the amount of elemental zinc per mg of zinc sulphate powder, resulting in slow and incomplete response to the treatment