Author/Authors :
Farajzadeh, Saeedeh kerman university of medical sciences - Department of Dermatology Pediatric Dermatology, ايران , Shahesmaeili, Armita kerman university of medical sciences - School of Medicine, ايران , Bazargan, Nasrin kerman university of medical sciences - Department of Pediatric Immunology Allergy, ايران , Mohebbi Poorkani, Zahra kerman university of medical sciences - School of Medicine, ايران , Karaminejad, Zakiyeh kerman university of medical sciences - School of Medicine, ايران , Aghaei, Hamideh kerman university of medical sciences - School of Medicine - Department of Dermatology, ايران , Pourdamghan, Nasim kerman university of medical sciences - School of Medicine, ايران
Abstract :
Background Earlier studies on breastfeeding (BF) and atopy in infants have yielded contradictory results. Objective To evaluate the relationship between duration of BF and developing of AD. Patients and methods Seven hundred fifty infants between 2 to 3 years old from kindergartens of Kerman, Iran were enrolled in this cross-sectional study. Data were obtained by questionnaires. Diagnosis of atopic dermatitis (AD) was made according to UK Working Party criteria. Results There was a significant association between duration of BF and the risk of AD (OR=0.93, 95% CI=0.90-0.96). Early supplement feeding increased the risk of AD (OR=0.69, 95% CI=0.52-0.92). The adjusted odds ratios of variables show that a positive family history of atopy, contact with smoke during pregnancy, suffering from asthma and rhinoconjunctivitis increased the risk of AD in infants. On the other hand, having elder siblings and taking oral contraceptive pills by mother decreased the risk of AD. Conclusion Our results suggest that duration of BF has a protective effect against developing AD in infants. We recommend prolonged BF in all infants for protection against AD
