Author/Authors :
Koley, Sankha North Bengal Medical College - Department of Dermatology, India , Choudhary, Sanjiv V. Jawaharlal Nehru Medical College - Department of Dermatology, India , Choudhury, Soumen Barddhaman Medical College - Department of Ophthalmology, India , Sharma, Shilpi North Bengal Medical College - Department of Dermatology, India , Mukherjee, Tanmoy North Bengal Medical College - Department of Dermatology, India , Khan, Kalyan North Bengal Medical College - Department of Pathology, India
Abstract :
Xeroderma pigmentosum (XP) occurs due to molecular defects in the genes involved in nucleotide excision repair of ultraviolet-induced DNA lesions. Patients with XP have a risk of developing skin cancer about 1000 times more than that of the general population. We report a classical presentation in a 6-year-child and advanced squamous cell carcinoma in a 24-year old man.
Keywords :
Xeroderma pigmentosum , poikiloderma , photosensitive rash , squamous cell carcinomas.
