Author/Authors :
Shidfar, F. iran university of medical sciences - School of Health - Department of Nutrition, ايران , Baghai, N. university of tehran - School of Health - Department of Nutrition, تهران, ايران , Keshavarz, A. university of tehran - School of Health - Department of Nutrition, تهران, ايران , Ameri, A. iran university of medical sciences - School of Health - Department of Nutrition, ايران , Shidfar, S. University of Massachusetts - Memorial Hospital, United States of America
Abstract :
In a case–control study the vitamin C status of 50 adults with chronic controlled asthma was compared with that of 50 randomly selected healthy controls. Vitamin C intake was assessed by 3-day dietary recall, and plasma and leukocyte vitamin C concentrations were measured colorimetrically. A positive significant correlation was found between plasma vitamin C and dietary vitamin C intake. Plasma and leukocyte vitamin C levels were significantly lower in the asthma group. Plasma vitamin C was deficient ( 0.4 mg/dL) in significantly more patients than controls (38.0% versus 0%) and leukocyte vitamin C ( 20 µg/108 leukocytes) was deficient in 92.0% of asthmatics versus 8.0% of controls. A significant association was observed between duration of asthma and plasma vitamin C level.