Author/Authors :
Hosseini, S.M.H. Razi Vaccine and Serum Research Institute - Department of Immunology, ايران , Hatam, G.R. shiraz university of medical sciences - School of Medicine - Department of Parasitology and Mycology, ايران , Ardehali, S. shiraz university of medical sciences - School of Medicine - Department of Parasitology and Mycology, ايران
Abstract :
Leishmania parasites were isolated after 13 and 8 years from the unhealed lesions of 2 soldiers who had been immunized against leishmaniasis during the war between Iraq and the Islamic Republic of Iran. Isoenzyme characterization on these isolates using 11 enzyme systems was carried out and the results were compared with the enzyme profiles of the original isolates of L. major used for leishmanization. Minor enzymatic differences in glucose-6-phosphate dehyrognase and phosphoglucomutase were observed but otherwise the strains appeared unchanged.