Author/Authors :
Tomi, Ivan Hameed R. University of Al-Mustansiriya - College of Sciences - Department of Chemistry, Iraq , Al-Daraji, Ali Hussein R. University of Al-Mustansiriya - College of Sciences - Department of Chemistry, Iraq , Al-Qaysi, Raya Raad T. University of Al-Mustansiriya - College of Sciences - Department of Chemistry, Iraq , Hasson, Mohammed Mujbel University of Al-Mustansiriya - College of Sciences - Department of Chemistry, Iraq , Al-Dulaimy, Khlood Hamed D. University of Al-Mustansiriya - College of Sciences - Department of Biology, Iraq
Abstract :
In this study we synthesized the new compounds containing bis-1,3,4-thiadiazole 3(A-D)n through many eaction steps (cyclization, diazotiazation and etherification respectively). The compounds have been characterized by melting point, FTIR and 1HNMR data. All the synthesized compounds have been evaluated in vitro for their antimicrobial activities against several microbes like: Escherichia coli, Klebsiellia pneumonia, Pseudomonas aerugenosa, Serratia marscens and Staphylococcus aureus and the results showed that some of these compounds have very good antibacterial activity.