Author/Authors :
Alizadeh, A. shahid beheshti university of medical sciences - Research Centre for Gastroenterology and Liver Disease, تهران, ايران , Ranjbar, M. hamadan university of medical sciences - Department of Infectious Disease, ايران , Kashani, K.M. hamadan university of medical sciences - Department of Community Medicine, ايران , Taheri, M.M. hamadan university of medical sciences, ايران , Bodaghi, M. hamadan university of medical sciences, ايران
Abstract :
We examined the therapeutic effects of albendazole compared to metronidazole in 120 patients with giardiasis in Hamdan. Patients were randomized to receive albendazole (400 mg, once daily for 5 days) or metronidazole (250 mg, 3 times a day for 5 days). Demographic data of the patients, results of stool exaamination for Giardia trophozoites before and after treatment, and drug side-effects were recorded. After treatment 6 (10.0%) of the albendazole group had trophozoites compared with 14 (23.3%) of metronidazole group (P 0.05). Patients in the albendazole group had fewer side-effects while 43.3% of the metronidazole group experienced a metallic taste and 35.0% experienced loss of appetite. Albendazole is an easy, safe and effective treatment for giardiasis.
