Author/Authors :
Ghaffarifar, F. tarbiat modares university - Medical School - Department of Parasitology, تهران, ايران , Jorjani, O. tarbiat modares university - Medical School - Department of Parasitology, تهران, ايران , Mirshams, M. tehran university of medical sciences tums - Razi Hospital - Department of Dermatology, تهران, ايران , Miranbaygi, M.H. tarbiat modares university - Technical and Engineering School - Department of Medical Engineering, تهران, ايران , Hosseini, Z.K. Razi Hospital, ايران
Abstract :
We assessed the effectiveness of photodynamic therapy in the treatment of cutaneous leishmaniasis in 5 patients. Delta-aminolevulinic acid in a water-in-oil emulsion was applied to the lesions and irradiation was performed. The treatment was repeated once a week for a month. Each time, direct smears of the lesions were prepared and cultured in NNN media. In direct staining, smears showed no amastigotes after 1 or 2 sessions. Healing and cosmetic outcome after photodynamic therapy was excellent. Only mild local inflammatory reaction was noted with no scarring and 4 months after the last treatment session, there were no clinical signs of recurrence.
