Author/Authors :
Wei, Lei Department of Nephrology - Xijing Hospital - Xi'an - Shaanxi 7100032, China , Wang, Hanmin Department of Nephrology - Xijing Hospital - Xi'an - Shaanxi 7100032, China , Wang, Di Department of Nephrology - Xijing Hospital - Xi'an - Shaanxi 7100032, China , Ma, Feng Department of Nephrology - Xijing Hospital - Xi'an - Shaanxi 7100032, China , Li, Li Department of Nephrology - Xijing Hospital - Xi'an - Shaanxi 7100032, China , Sun, Shiren Department of Nephrology - Xijing Hospital - Xi'an - Shaanxi 7100032, China
Abstract :
Primary renal lymphoma(PRL) is an extremely rare form of extranodal lymphoma andexhibitsas single (10-20%), multifocal nodules (60%), renal invasion from contiguous retroperitoneal disease (25-30%), diffuse infiltration (20%) or perirenal involvement (10%)[1] .Here we report a case of bilateral primary renal lymphoma in a 13 yearold boy who presented with homogenous nephromegaly and acute interstitial nephritis(AIN).The renal biopsy
revealed primary renal T lymphoblastic lymphoma. Hyper-CVAD regimen was initiated and the renal function
had been recovered after the first round of chemotherapy. To our knowledge, there have only been three reports
of primary renal T lymphoblastic lymphoma including ours so far. All the three patients were young and showed
as AIN and bilateral renal enlargement. We also reviewed 16 cases of PRL presenting with AIN and enlarged kidneys
that have been reported since 1997. Although PRL is quite rare, it must be taken into account when making
a differential diagnosis of AIN. Renal biopsy is the gold standard and intensive chemotherapy can preserve the renal function.
