Author/Authors :
Tabarsi, P. National Research Institute of Tuberculosis and Lung Disease, ايران , Mirsaeidi, S.M. National Research Institute of Tuberculosis and Lung Disease, ايران , Amiri, M. National Research Institute of Tuberculosis and Lung Disease, ايران , Mansouri, S. .D. National Research Institute of Tuberculosis and Lung Disease, ايران , Masjedi, M.R. National Research Institute of Tuberculosis and Lung Disease, ايران , Velayati, A.A. National Research Institute of Tuberculosis and Lung Disease, ايران
Abstract :
This case series describes the clinical and laboratory profile of 15 patients with tuberculosis (TB) HIV coinfection admitted to a referral centre in the Islamic Republic of Iran. Most of the patients (13) were male; the mean age was 36.9 years. Intravenous drug use was the route of transmission for all males and heterosexual intercourse for the 2 females; 12 patients had a history of imprisonment. All patients had pulmonary TB; 13 were smear-positive and all except 1 had atypical radiological presentation. Drug-induced hepatitis occurred in 3 patients and 12 had hepatitis C coinfection. Five patients died. The mean CD4 count was 229.2 (SD 199.5) cells/mm3 and 78.6% had CD4 count 350. TB may be an AIDS-defining illness in this country.