Author/Authors :
al-hindi, hayder abdul- amir maki babylon university - faculty of pharmacy toxicology, college of pharmacy, Iraq , al-saad, shukry faez babylon university - college of medicine - dep. of medicine, Iraq , zwain,, basim mh. jabir ibn hayyan medical university - faculty of medicine, Iraq , jaber, thekra abid al-kashwan middle euphrates unit for cancer researches - medical genetics lab, Iraq
Abstract :
Myocardial infarction (MI) is a disorder that could be a reason for morbidity mortality. Effective early identification is crucial for management. One analytical technique for the diagnosis of MI is evaluating plasma troponin (Tn) values. Bearing in mind the problems of blood aspiration from patients, a noninvasive practice like measuring of saliva Tn can be used as an alternative way. The present works aims to inspect variations in plasma salivary Troponin I (TnI) measurements in AMI patients. Methods: The study involved 100 patients diagnosed as AMI by physicians. After obtaining their agreement, both salivary plasma TnI levels was assessed by saliva blood sampling consequently by means of; VIDUS® techniques and kits. Results: The mean age of patients was 56.5years and 79% of patients were male. There was week positive correlation between blood and serum troponin levels (r=0.1, P 0.05). The mean troponin level in serum was 8.07ng/L and troponin level in salvia was 0.16 ng/L showing a steady increase in saliva and blood during the process of AMI. There was no significant correlation of both serum salivary TnI with increasing age or with gender differences. Conclusion: There was week positive significant correlation between S TnI Sal TnI concentrations showing a steady increase in saliva and blood during the process of AMI.