Title of article
Eosinophilic cationic protein: is it useful in assessing control of childhood asthma?
Author/Authors
Zedan, M. University of Mansoura - Faculty of Medicine - Allergy, Respiratory and Clinical Immunology Unit, Egypt , Settin, A. University of Mansoura - Faculty of Medicine - Department of Paediatrics, Egypt , El-Chennawi, F. University of Mansoura - Faculty of Medicine - Clinical Pathology and Immunology Unit, Egypt , El-Desouky, T. University of Mansoura - Faculty of Medicine - Allergy, Respiratory and Clinical Immunology Unit, Egypt , Nasef, N. University of Mansoura - Faculty of Medicine - Department of Paediatrics, Egypt , Fouda, A. University of Mansoura - Faculty of Medicine - Department of Paediatrics, Egypt
From page
1045
To page
1049
Abstract
This study evaluated peripheral eosinophil and serum eosinophilic cationic protein (s-ECP) levels asmarkers of asthma control. A total of 38 children with asthma (16 controlled and 22 partially controlled) were compared with 16 age- and sex-matched healthy children. Total asthma cases had higher eosinophil counts and s-ECP levels than healthy children and partially controlled asthmatics had significantly higher levels of both markers than controlled asthmatics. Controlled asthma cases showed non-significant changes in both parameters versus healthy children. A negative correlation was noted between degree of asthma control and both eosinophil counts and s-ECP levels (r = –0.60 and –0.75 respectively). s-ECP as well as peripheral eosinophil count may be helpful in the assessment of asthma control.
Journal title
Eastern Mediterranean Health Journal
Journal title
Eastern Mediterranean Health Journal
Record number
2641786
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