Author/Authors :
Mashayekhi, S.O. tabriz university of medical sciences - Faculty of Pharmacy,National Public Health Management Centre - Clinical Pharmacy Department, ايران , Ghandforoush-Sattari, M. tabriz university of medical sciences - Haematology Oncology Research Centre, Faculty of Pharmacy - Department of Pharmacology and Toxicology, ايران , Baghdadchi, M.E. tabriz university of medical sciences - Faculty of Medicine, ايران , Kheyri, M. tabriz university of medical sciences - Heart Research Centre, ايران
Abstract :
We aimed to study the prevalence of the side-effects of statins among Iranians patients admitted to a cardiac-specialized hospital and had taken statins prior to hospitalization. Data was collected between September 2007 and March 2008 and 200 patients were enrolled. A questionnaire was completed using the patients’ records and by interviewing the patients. The mean age of the participants was 61.5 (SD 12.3) years and 63% were males. The most commonly used statins was atrovastatin (99% of the patients). In all, 63.5% of the participants reported experiencing side-effects due to statins. The reported side-effects were respiratory (4%) and gastrointestinal effect (18.5%), headache (16.5%), rash (0.5%) and allergic reactions (5%); 9.5% reported muscle-related side-effects such as myalgia. Although, the clinical benefits outweigh the small risk of liver failure and myopathy, clinicians should be aware of the side-effects of statins.
