Author/Authors :
Abbass, F. Faculté des Sciences et Techniques de Fès, Maroc , Bennis, S. CHU Hassan II de Fès - Faculté de Médecine et de Pharmacie, Maroc , Znati, K. CHU Hassan II de Fès - Service d’Anatomie pathologique, Maroc , Akasbi, Y. CHU Hassan II de Fès - Service d’Oncologie médicale, Maroc , Amrani, J.K. Faculté des Sciences et Techniques de Fès, Maroc , El Mesbahi, O. CHU Hassan II de Fès - Service d’Oncologie médicale, Maroc , Amarti, A. CHU Hassan II de Fès - Service d’Anatomie pathologique, Maroc
Abstract :
In a retrospective study of 265 patients with breast cancer over 3 years (January 2007–September 2009) we examined the epidemiological profile of breast cancer to determine the impact of biological and prognostic factors on survival over 3 years and on the epidemiology of this cancer. Estrogen (RE), progesterone (RP) and human epidermal growth factor receptors (HER2) were evaluated and RE/RP/HER2 status determined. The patients were young (median age 45 years). Invasive tumours were found in 95.5% of the women. The average tumour size was big [3.6 (SD 2.6) cm] and only 14% were histological grade I. Large tumour size and high histological grade were independent of patient’s age. Overall survival at 3 years was only 49% for the RE–/RP–/HER2– subtype and 75% for the RE–/RP–/HER2+ subtype, while it was 96% for the RE+/RP+/HER2– subtype. The young age, large tumour size and high histological grade in our population suggest a lack of awareness of women about breast cancer.
