Author/Authors :
Shamsizadeh, A. ahvaz jundishapur university of medical sciences - Health Research Institute, Infectious and Tropical Diseases Research Centre, Aboozar Children’s Hospital, Faculty of Medicine, اهواز, ايران , Nikfar, R. ahvaz jundishapur university of medical sciences - Health Research Institute, Infectious and Tropical Diseases Research Centre, Faculty of Medicine, اهواز, ايران , Yusefi, H. ahvaz jundishapur university of medical sciences - Aboozar Children’s Hospital,Faculty of Medicine, اهواز, ايران , Abbasi-Montazeri, E. ahvaz jundishapur university of medical sciences - Facultyof Medicine - Department of Microbiology, اهواز, ايران , Cheraghian, B. ahvaz jundishapur university of medical sciences - Faculty of Health - Department of Epidemiology, اهواز, ايران
Abstract :
Although pertussis is a vaccine-preventable infection, vaccine-induced immunity is not lifelong and booster doses are recommended according to national disease epidemiology. The aim of this study was to evaluate pertussis-IgG levels in school-aged students in Ahvaz, south-west Islamic Republic of Iran. In a descriptive, crosssectional study, blood samples were obtained from 640 students (382 boys and 258 girls) aged 6–17 years during 2010–2011. All students had received a full course of pertussis whole-cell vaccination at ages 2, 4, 6 and 18 months and 4–6 years. Using a Bordetella IgG ELISA kit, pertussis-IgG was detected in 301 (47.0%) students. No statistically significant differences in pertussis-IgG levels were found between girls and boys or across different age groups. The findings show that the overall level of pertussis-IgG seropositivity was unacceptable. Booster vaccination with an acellular pertussis vaccine should be considered in adolescents and/or adults in our region.
