Title of article :
ESTIMATION ACTIVITY OF LAP IN PATIENT S WITH TYPE 2 DIABETES BY USING LEUCINE AMIDE AS SUBSTRATE
Author/Authors :
Khaleel, Fayhaa M. Baghdad University - College of Science for Women - Department of Chemistry, Iraq , Mohamad, Tagreed U. Baghdad University - College of Education Ibn Al-Haytham - Department of Chemistry, Iraq , Hameed, Areej Sh. Baghdad University - College of Science for Women - Department of Chemistry, Iraq
Abstract :
This study was performd on 50 serum specimens of patients with type 2 diabetes, in addition, 50 normal specimens were investigated as control group. The activity rate of LAP in patients (560.46±10.504) I.U/L and activity rate of LAP in healthy(10.58± 4.39)I.U/L.The results of the study reveal that Leucine aminopeptidase (LAP) activity of type 2 diabetes patient s serum shows a high signifiacant increase (p 0.001) compare to healthy subjects. Addition preparation leucine amide as substrate of LAP, identification melting point and spectra by FTIR.
Keywords :
Leucine Aminopeptidase(LAP) , Diabetes mellitus.
Journal title :
Al-Nahrain Journal Of Science
Journal title :
Al-Nahrain Journal Of Science
