Author/Authors :
Al-Naimy, Ebtehal H. Al –Nahrain University - Biotechnology Research Center, Iraq , Al-Amery, Maythem M. Baghdad University - College of Science for Women - Biology Department, Iraq , Al-Azy, Ruqia M. Al-Nahrain University - College of Science - Biotechnology Department, Iraq
Abstract :
This study was designed to evaluate the antibacterial and cytogenetic effect of Cassia italica (Senna) on metaphase index and micronucleous formation in polychromatic erythrocytes of bone marrow cells of mice. Results showed that Cassia italica leaves methanolic extract caused a significant inhibition in growth of E.coli and Staphylococcus auerous and Candida albicans especially at high concentrations in comparison with the negative control (Distilled water) and positive controls (Tetracycline). On the other hand the results showed that Cassia italica extract caused a significant increase in metaphase index and a significant decrease in micronucleous formation in bone marrow of mice in comparison with the negative control (Distilled water) and positive controls (Cyclophosphomide).
