Enhanced One-Pot Microwave Efficient Synthesis of Some Pyrrolidine-2, 5-Diones, Butenamides and their Sulfonamide Derivatives Versus Conventional Thermal Heating Technique

DUE TO the highly important medical applications and wide biological activities of pyrrolidines, butenamides, and their sulfonamide derivatives, such as bacteriocides, fungicides, and insecticides, compounds (4-42) were synthesized from condensation of α, β-unsaturated anhydrides (1-3), with the corresponding amines, using either enhancing microwave irradiation heating or the conventional thermal heating technique in order to compare between their efficiency.