Author/Authors :
MUSHTAQ, NOUSHEEN University of Karachi - Faculty of Pharmacy - Department of Pharmaceutical Chemistry, Pakistan , SAIFY, Z.S. University of Karachi - HEJ Research Institute of Chemistry, Pakistan , AKHTAR, SHAMIM University of Karachi - Faculty of Pharmacy - Department of Pharmaceutical Chemistry, Pakistan , ARIF, MUHAMMAD University of Karachi - Faculty of Pharmacy - Department of Pharmaceutical Chemistry, Pakistan , HAIDER, SAIDA University of Karachi - Department of Biochemistry, Pakistan , SABA, NAZISH University of Karachi - Faculty of Pharmacy - Department of Pharmaceutical Chemistry, Pakistan
Abstract :
In the present study some compounds of 4-(1-Pyrrolidinyl) Piperidine (I) have been synthesized. Structures of compounds were confirmed by using HNMR, IR, Mass and UV spectrophotometer techniques. All the derivatives (II, III, IV and V) and the parent compound (I) at the dose of 100 mg/kg were evaluated for their effect on plasma glucose level. Compound (II) was the only derivative which showed effect on plasma glucose level.
