Title of article :
ANTIINFLAMMATORY, ANALGESIC AND ANTIPYRETIC ACTIVITIES OF ETHANOLIC ROOT EXTRACT OF CROTON ZAMBESICUS
Author/Authors :
OKOKON, JUDE E University of Uyo - Department of Pharmacology and Toxicology, Nigeria , NWAFOR, PAUL A University of Uyo - Department of Pharmacology and Toxicology, Nigeria
Abstract :
The ethanolic root extract of C. zambesicus (27-81mg/kg) was evaluated for antiiflammatory, analgesic and antipyretic properties in mice. The extract (27-81mg/kg) demonstrated a weak antiinflammatory activity. However, a significant (P 0.01-0.001) analgesic and antipyretic activities were observed in all the experimental models tested. The extract may be exerting its effects through central mechanisms. These findings confirms its ethnomedical use in the treatment of malarial-associated symptoms.
Keywords :
Antiinflammatory , analgesic , antipyretic , Croton zambesicus
Journal title :
Pakistan Journal Of Pharmaceutical Sciences
Journal title :
Pakistan Journal Of Pharmaceutical Sciences
