Title of article :
In vitro tumor cytotoxic activities of extracts from three Liriodendron plants
Author/Authors :
Chen, Jin-Hui Ministry of Education of China, Nanjing Forestry University - Key Laboratory of Forest Genetics and Biotechnology, China , Yang, Guo-Xu Nanjing University of Science and Technology - School of Environmental and Biological Engineering, China , Ding, Qiang Nanjing Medical University - First Affiliated Hospital - Department of Breast Surgery, China , Xia, Tian-Song Nanjing Medical University - First Affiliated Hospital - Department of Breast Surgery, China , Shi, Jisen Ministry of Education of China, Nanjing Forestry University - Key Laboratory of Forest Genetics and Biotechnology, China , Jia, Ai-Qun Nanjing University of Science and Technology - School of Environmental and Biological Engineering, China
Abstract :
The extracts prepared from Liriodendron tulipifera Linn., L. chinense (Hemsl.) Sarg., and their hybrid L. chinense x L. tulipifera, were investigated for their cytotoxic abilities in vitro against five human cancer cell lines: MDAMB- 231 and MCF-7 breast cancer cells, SGC-7901 gastric cancer cells, HuH-7 hepatocarcinoma cells, and HCT-15 colon carcinoma cells, and then measured their phenols and alkaloids contents. Of these plant extracts, some of them, especially the lower polar extracts from barks, exhibited potent cytotoxic effects on five tested tumor cell lines.
Keywords :
Liriodendron , polyphenol , alkaloid , tumor cells , cytotoxic activity
Journal title :
Pakistan Journal Of Pharmaceutical Sciences
Journal title :
Pakistan Journal Of Pharmaceutical Sciences
