Coronary artery disease in patients undergoing valve replacement at a tertiary care cardiac centre

Objective: To determine the prevalence of coronary artery disease in patients undergoing valve surgery at a tertiary care cardiac centre.Methods: The medical records of 144 consecutive patients who underwent mitral, aortic or dual (mitral and aortic) valve replacement surgery at the Tabba Heart Institue between January 2006 to December 2008 were retrospectively reviewed. All patients underwent coronary angiogram. Significant coronary artery disease (CAD) is defined as coronary stenosis of 50%.Results: There were 74 (51.4%) males and 70 (48.6%) females in the study. The mean age was 51.64 ± 11 years. Of all, 73 (50.7%) underwent mitral valve replacement, 47 (32.6%) had aortic and 24 (16.7%) had dual valve replacement.Out of 144 patients, 99 (68.8%) had 50% coronary stenosis and remaining 45 (31.3%) had 50% stenosis. In patients who had undergone mitral valve replacement (MVR), significant coronary disease was found in 32.9%, whereas in patients who had undergone aortic valve replacement (AVR) and dual valve replacement (DVR) the prevalence of coronary disease was 31.9% and 25% respectively.Conclusions: Our results suggest that the overall prevalence of coronary artery disease in patients undergoing valve surgery in our population is comparable with prevalence reported in international data.