Title of article
Evidence Based Medicine: What is the Role of B-vitamins in stroke prevention in Pakistan?
Author/Authors
Khan, Maria Aga Khan University Hospital - Fellow International Cerebrovascular Translational Clinical Research Training Program, Stroke Service, Pakistan , Raza, Emmon Aga Khan University Hospital - Medical College, Pakistan , Kamal, Ayeesha Kamran Aga Khan University Hospital - Stroke Service and Vascular Fellowship Program, Pakistan
From page
825
To page
826
Abstract
Why is this study important? A person who has had a stroke or transient ischaemic attack has a higher risk of experiencing similar major vascular events in the future. This risk remains high despite aggressive medical and surgical management. An elevated homocysteine level in plasma is a known risk factor for major vascular events and it is well established that daily long-term supplementation with Vitamin B12 and Folic acid lowers these levels by a significant proportion. The VITATOPS trial was undertaken to test whether this reduction in homocysteine with vitamin supplementation translates into actual reduction in recurrent vascular events in patients with recent stroke (ischaemic or haemorrhagic) or TIA.
Journal title
Journal of the Pakistan Medical Association (Centre) JPMA
Journal title
Journal of the Pakistan Medical Association (Centre) JPMA
Record number
2651510
Link To Document