Abstract :
This experiment was designed to study the effect of flavonoid extracted from Hawthorn (crataegus oxyacantha) on some hematological parameters in female mice. The experiment was performed on fifteen female mice which were divided randomly into three equal groups (5/group) and were treated daily as follows for four weeks: the first group was received distilled water and served as control, mice of the second group (TR1R) was administrated 9 mg /kg B.W. flavonoids and the third group (TR2R) was administrated 18 mg /kg B.W. flavonoids for four weeks. Blood samples were collected at the end of the experiment to study the following parameters:-RBCs count, PCV ratio, Hb concentration, differential leukocytes count, MCV, MCH and MCHC. The results showed that animals treated with flavonoids extracted from Hawthorn (TR1R and TR2R) have not significant differences (P 0.05) in RBC count, MCV and MCH, as compared to control. There was significant decrease in packed cell volume in both treated groups as compared to control but there was significant increment (P 0.05) in Hb concentration of third group (TR2R) as compared to second (TR1R) and control groups. The results also showed marked increased of the MCHC percentage in both second and third treated group as compared to control. The effect of flavonoids extracted from hawthorn showed significant decrease of neutrophil percentage and significant increase of lymphocyte percentage in treated groups as compared to control, while there was no significant increase in the percentage of monocytes and eosinophils.
