Citicoline in the treatment of acute ischaemic stroke: an international, randomized, multicentre, placebo-controlled study (ICTUS trial)Is the use of Citicoline is beneficial for acute ischaemic stroke?

Stroke is the leading cause of disability in the world population Citicoline is an exogenous form of cytidine 5 - diphosphatecholine, an important component of the cellular membrane, is a medication believed to have combined neurovascular protection and repair effects. It is extensively studied in many clinical trials in patients including ischaemic stroke however promising results on meaningful clinical recovery and reduction of disability is lacking.