Author/Authors :
Hossain, Nazli Dow University of Health Sciences - Civil Hospital Karachi - Department of Obstetrics Gynecology Unit-3, Pakistan , Farzana, Tasneem National Institute of Blood Diseases, Pakistan , Khan, Nusrat Hasan Dow University of Health Sciences - Civil Hospital Karachi - Department of Obstetrics Gynecology Unit-3, Pakistan , hussein, alyaa razooqi National Institute of Blood Diseases, Pakistan , James, Andra H Duke University - Medical Center - Department of Obstetrics and Gynecology, USA
Abstract :
The prevalence of menorrhagia in adolescent populations with bleeding disorders varies between 14% to 48%. The common conditions associated with menorrhagia include von Willebrand disease (VWD), platelet function disorders and coagulation factor deficiencies. The majority of studies, which have been conducted in the West, report VWD, as the most common inherited bleeding disorder leading to menorrhagia, whereas studies from South-East Asia have found platelet function disorder as the leading inherited bleeding disorder in women with menorrhagia. The other common conditions which can lead to increased blood loss in this age group are anovulatory bleeding and hormonal disorders. We report here three cases of adolescent menorrhagia due to platelet function disorders, along with review of literature.